Southwest Illinois Vacations from $217

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Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

The Latest Southwest Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport
Save 100% on your flight
$217
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
7.6/10 Good! (1,006 reviews)
My family stayed at this establishment recently. We paid $325 for a family suite as we had 7 people staying. The room was not very clean. We took our kids to the pool where there was no pool towels at all. We went to the front desk to obtain some pool towels and they didn’t have any either. They gave us gym towels (the size you’d use to wipes sweat off your face) to use for the pool…The pullout bed had no bedding on it or in the room to utilize (even though we had 7 people on our check in list). When we went up front to get sheets and pillows, we were given 2 fitted sheets and a blanket with no pillows. Then for breakfast they had no protein items except boiled eggs. There was cereal, oatmeal, and waffles and a few others items. And it also was not ready at their 7am breakfast time. It was about 7:30 by the time these items were actually prepared. For an establishment that advertises this great breakfast with great amenities we won’t be staying there again. It was not worth the money we paid at all.

Reviewed on Aug 9, 2026

The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$322
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,672 reviews)
Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

Save 100% on your flight
$551
per person
Sep 27 - Oct 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
10/10 Exceptional! (1 review)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it

Reviewed on Aug 7, 2026

The Cheshire

The Cheshire

Save 100% on your flight
$299
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
When checking in, the staff woman was less than friendly. There seemed to be a situation with another upset guest that may have caused the unpleasant nature. Once we entered the room, we noticed right away a musty smell. The AC did not seem to be working correctly. Though it never got hot, it also never got any cooler. The furniture had visible stains and a few of the pillow cases had staining as well. The pillows themselves are downed pillows and once you lay on them, they flatten out thin. We requested a few extra pillows that were supposed to be brought to our room which never arrived. We requested more towels which were also supposed to be brought to our room which also never arrived. Breakfast on morning one for us which was Sunday was great, however it was apparent that the fruit and pastries were being reused daily and by our check out morning on Tuesday they were no good. The pool area was decent. You have to reserve the canopy so it was unusable to us. Overall, our stay was okay. I wouldn’t say it was awful but I wouldn’t say it was great either. We don’t intend on staying in the future.

Reviewed on Aug 9, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$296
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9/10 Wonderful! (2,006 reviews)
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Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

A tall water tower with a red and white striped top, surrounded by trees and a clear blue sky.

Uptown

If you're spending some time in Uptown, World's Largest Catsup Bottle and Kruta Bakery are top sights worth seeing.

A river with a bridge, a city skyline, and a large industrial area.

Alorton

Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Arsenal BG Ballpark or Gateway Arch.

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Mulberry Hills

While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

Stay near popular Southwest Illinois attractions

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
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O'Fallon Family Sports Park

8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
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World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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DuQuoin State Fairgrounds

8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
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Southwest Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$88 nightly
$100 total
Aug 16 - Aug 17
Total with taxes and fees
Drury Inn & Suites St. Louis Fairview Heights
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$80 nightly
$90 total
Aug 16 - Aug 17
Total with taxes and fees
Best Western St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
$125 total
Aug 30 - Aug 31
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
See all 759 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southwest Illinois Vacation Packages

Southwest Illinois Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

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