Southwest Illinois Vacations from $235
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Your Southwest Illinois Vacation
When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.
The Latest Southwest Illinois vacation packages
Hilton Garden Inn Chesterfield
Reviewed on Oct 26, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Reviewed on Nov 13, 2025
Where to stay in Southwest Illinois
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Discover the most popular places to visit in Southwest Illinois
Southern Illinois University
Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
Giant City State Park
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
Ferne Clyffe State Park
You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.
Southwest Illinois Hotel Deals
Super 8 by Wyndham O'Fallon
Everything ok nice price
Reviewed on Nov 8, 2025
Drury Plaza Hotel Mt. Vernon
Friendly front desk, clean room, felt safe
Reviewed on Nov 11, 2025
Quality Inn & Suites near St. Louis and I-255
Staff very cordial. We were satisfied with our stay. Location is near food and commerce options. LOTS of handicap parking = the WHOLE front row near the building. Trim strip missing in bathroom made it appear less than clean. HARD TO GET IN & OUT OF TUB FOR BATH as only one puny grab bar = likely ...
Reviewed on Nov 4, 2025
Find the Best Southwest Illinois Vacation Packages
Southwest Illinois Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
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