Name: Drury Plaza Hotel Mt. Vernon
Price range: $127 total
Rating: 9.6

Photo by Southernmost Illinois Tourism Bureau

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Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois

Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

1 out of top 10 points of interest in this area

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Discover the most popular places to visit in Southwest Illinois

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Giant City State Park

4.5/5(78 reviews)

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

Ferne Clyffe Waterfall Detail
Goreville IL
#detail

Ferne Clyffe State Park

4.5/5(10 reviews)

You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.

Southwest Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Fully refundableReserve now, pay when you stay

$94 nightly

$106 total

Mar 2 - Mar 3

Total with taxes and fees

9.2/10 Wonderful! (1,008 reviews)

Yes.

Reviewed on Feb 24, 2026

Drury Inn & Suites Marion

2706 W DeYoung St Marion IL

Fully refundableReserve now, pay when you stay

$99 nightly

$119 total

Mar 13 - Mar 14

Total with taxes and fees

9.4/10 Exceptional! (1,006 reviews)

The room was spotless. The staff were great. The morning breakfast and evening buffet were tasty and well maintained.

Reviewed on Feb 24, 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Fully refundableReserve now, pay when you stay

$113 nightly

$127 total

Mar 8 - Mar 9

Total with taxes and fees

9.6/10 Exceptional! (1,663 reviews)

Everything was amazing

Reviewed on Feb 24, 2026

See all 744 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.